A question we often get is: can you combine CBD oil with medications? Although CBD is becoming increasingly popular due to positive reports about its effects, it is important to understand what happens when you use CBD while taking medications. In this blog, we discuss the possible benefits, dangers, and important considerations of combining CBD oil with medications.
What is CBD oil?
CBD oil is a product derived from the hemp plant and is used for various health benefits. Unlike cannabis oil, CBD oil contains a minimal THC content, so it does not make you high. The use of CBD oil is a natural way for many people to reduce complaints such as stress, pain, and sleep problems.
Why do people want to combine CBD with medications?
Many people with (chronic) complaints use medications to reduce their symptoms. At the same time, they hear positive stories about CBD and want to try it as additional support. Combining CBD and medications can be beneficial in some cases, but it also carries risks that you need to understand before starting.
How are medications processed in the body?
Medications, like food, are processed by your body. This mainly happens in the liver through the CYP450 system, a group of enzymes responsible for breaking down substances such as medications and cannabinoids. The CYP450 system consists of 57 enzymes, of which 15 are important for processing medications.
When medications are broken down by this system, they are eventually excreted via the bile or kidneys. However, the CYP450 system is sensitive to disruptions, and certain substances — such as CBD — can slow down this process.
How does CBD affect the breakdown of medications?
CBD can inhibit the CYP450 system, which means medications are broken down more slowly. This can lead to an increase in the concentration of the medication in your blood, which can be both beneficial and dangerous:
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Benefits: In controlled situations, a higher concentration may mean you need less medication for the same effect.
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Danger: If the medication level becomes too high, side effects can occur. This is especially a risk with medications such as blood thinners, chemotherapy, or antidepressants.
Examples of medications and CBD
Some common medications that require caution when combined with CBD oil are:
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Blood thinners: CBD oil can affect the effectiveness of blood thinners such as warfarin. CBD oil and blood thinners always requires consultation with your doctor.
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Antidepressants: Combining CBD oil and antidepressants can change the effectiveness of your medications. Experiences with this vary per person.
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Painkillers: Drugs like paracetamol or diclofenac can work differently in combination with CBD.
Which medications do not mix well with CBD oil?
About 60% of medications are processed via the CYP450 system. Here is a list of drugs that require extra caution:
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Antibiotics
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Anti-epileptics
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Antidepressants
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Blood thinners
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Antipsychotics
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Statins
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NSAIDs
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Steroids
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Oral anti-diabetics
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Angiotensin II blockers
Always consult your doctor before using CBD in combination with these medications.
What are the risks of combining CBD and medications?
Combining CBD with medications can carry risks, such as:
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Side effects: An increased medication level can lead to side effects such as dizziness, nausea, or drowsiness.
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Unpredictable effect: The effectiveness of your medications can decrease or increase in an uncontrolled way.
How can you safely use CBD with medications?
Here are some steps to minimize the risk:
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Consult your doctor: This is the most important step. Discuss your plans with a medical professional familiar with your medical history.
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Begin with a low dose: Start with a low dose of CBD to see how your body reacts.
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Choose quality CBD oil: Use only CBD oil with a test report to be sure of the quality.
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Keep track of your symptoms: Note any changes in your symptoms or side effects and discuss them with your doctor.
What does CBD oil do to your blood pressure?
There are indications that CBD oil can help lower high blood pressure. This can be useful for people with hypertension, but it can also be a risk if you are already taking blood pressure medication. Always consult your doctor before using CBD if you take medication for your blood pressure.
Choose high-quality CBD oil
At Prohemp, we only offer high-quality CBD products that are tested for purity and quality. Our oils contain no or minimal THC, allowing you to safely benefit from the advantages of CBD. Always choose products with a test report and avoid cheap alternatives without clear information about the composition.
Want to start with CBD? Then choose a quality product with a test report, such as the CBD oil from ProhempThis way, you can safely discover what CBD can do for you.
Do you have questions? Contact our specialists for personal advice.